The Risk of Papillary Thyroid Cancer Is Increased Among First- to Third-Degree Relatives
نویسندگان
چکیده
Background The incidence of thyroid cancer—the most common endocrine cancer, mainly composed of papillary thyroid cancer (PTC; ~80%)—has increased worldwide over the past several decades. Known risk factors for thyroid cancer include a history of head and neck radiation, iodine deficiency or excess, and other thyroid disease. Although most cases of PTC are sporadic, a small proportion may be genetically linked. The objective of this study was to assess the familial risks of PTC using a large population database.
منابع مشابه
Establishing a familial basis for papillary thyroid carcinoma using the Utah Population Database.
IMPORTANCE Determining if relatives of patients diagnosed as having papillary thyroid carcinoma (PTC) are at increased risk of developing the same cancer--and if so, which relatives and to what degree--would help identify those who require closer clinical attention. This could lead to earlier cancer detection and improved prognoses. OBJECTIVE To define the familial risk of PTC using a unique ...
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